Clinical Studies
Committed to supporting further developments in cardiology, BIOTRONIK has been deeply involved in conducting clinical trials. Our scientific activities encompass a variety of topics in the field of cardiac rhythm management and cardiovascular intervention. In collaboration with international medical experts, we strive to continuously improve the diagnosis and treatment of cardiac and vascular diseases.
The databases below provide an overview of BIOTRONIK’s studies in cardiac rhythm management and cardiovascular intervention, along with related publications and resources.
Filter Clinical Studies
MATRIX¹
Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
ORIENT
Comparison of the angiographic result of the Orsiro stent with Resolute Integrity stent
PEACE
Pulsar efficacy - An all-comers registry: 12-month results
PEPPER
First-In-Human Trial - Paclitaxel-Releasing Balloon in Patients Presenting with In-Stent Restenosis
QP ExCELs
Sentus QP - Extended CRT Evaluation with Quadripolar Left Ventricular Leads
QP ExCELs (CRT-DX)
Novel Two-Lead Cardiac Resynchronization Therapy System Provides Equivalent CRT Responses with Less Complications than a Conventional Three-Lead System: Results from the QP ExCELs Lead Registry
Shaik N et al., Journal of Cardiovascular Electrophysiology, May 2020.
doi: 10.1111/jce.14552
RM-ALONE
Safety and efficiency of a common and simplified protocol for pacemaker and defibrillator surveillance based on remote monitoring only: a long-term randomized trial
GARCIA FJ ET AL., EUROPEAN HEART JOURNAL 2019
SCAAR
Swedish Coronary Angiography and Angioplasty Registry
SCAAR
Long term outcome after treatment of de novo coronary artery lesions using three different drug coated balloons
SELENE HF
Combining home monitoring temporal trends from implanted defibrillators and baseline patient risk profile to predict heart failure hospitalizations (SELENE HF)
D’Onofrio A et al. Europace 2021
doi: 10.1093/europace/euab170.
SENSE
Subclinical atrial fibrillation detection with a floating atrial sensing dipole in single lead implantable cardioverter defibrillator systems: Results of the SENSE trial
THOMAS G ET AL., JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY 2019
doi: 10.1111/JCE.14081
SORT-OUT VII
BIOTRONIK Sirolimus-eluting Orsiro stent vs Terumo biolimus-eluting Nobori Stent
TASC D
Twelve months effectiveness analysis of the Pulsar-18 self-expanding nitinol stent in patients with critical limb ischemia
TASC D II
Evaluation of the 4 French Pulsar-18 self-expanding nitinol stent in long femoropopliteal lesions (TASC D II) – 12-month results
THINGS
The Role of Atrial Sensing for New-Onset Atrial Arrhythmias Diagnosis and Management in Single-Chamber Implantable Cardioverter Defibrillator Recipients: Results From the THINGS Registry
BIFFI M ET AL., JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY 2020
doi: 10.1111/jce.14396
TRUECOIN
Daily Remote Monitoring of Implantable Cardioverter-Defibrillators – Pooled Individual Patient Data from IN-TIME, ECOST, and TRUST Trials Suggest a Mechanism of Clinical Benefit
Hindricks et al., European Heart Journal 2017
TRUST
Efficacy and Safety of Automatic Remote Monitoring for Implantable Cardioverter-Defibrillator Follow-Up
Varma, Circulation 2012